Applications of AO168 in Medical and Food Contact Materials

Table of Contents

Applications of AO168 in Medical and Food Contact Materials

As global requirements for:

  • Food safety
  • Medical safety
  • Low migration
  • Low VOC
  • Long-term stability

continue to increase, the polymer additive industry is moving toward:

Higher purity, lower impurities, and stricter regulatory standards

Among these additives:

AO168 (Antioxidant 168)

as one of the most important phosphite secondary antioxidants, has been widely used in:

  • Medical plastics
  • Food packaging
  • Infusion devices
  • Medical tubing
  • Baby products
  • High-end food containers

and many other applications.

1. Why Medical and Food Materials Need AO168

Medical and food-contact materials are commonly made from:

  • PP
  • PE
  • PET
  • EVA
  • TPU
  • Engineering plastics

During:

  • High-temperature sterilization
  • Extrusion
  • Injection molding
  • Long-term storage

these materials are prone to:

  • Thermal oxidative degradation
  • Yellowing
  • Odor generation
  • Molecular chain scission

Therefore:

Highly effective stabilization systems are essential

AO168 can:

Rapidly decompose hydroperoxides (ROOH)

and prevent continuous polymer oxidation.

AO168 Mechanism Illustration

https://images.openai.com/static-rsc-4/w4zfd7cEA8iG4i7G5Vz-QJjyagdmsaBjC8TlOgjesRLHB-F9AMgnd7yiXyE2zbU2U641odgRNWQVUv2Zxpuu-w5p3DV8pGCmNr-DDQgW1gwdPADEeZy1e38cRvcnrTi6FBGLB9rLAH0zIlkOTNiIPBNumGmak7-Jkzs96TXzQ6Vk01Lijp-oRM69oysTzSQr?purpose=fullsizehttps://images.openai.com/static-rsc-4/Gqx8CuAXDOELHLvcYa39unXKpHPrFntFmTCvv1jByIyF8USy7D8PhEL7ChcmUzQbFyXUBwuWqrhPPtb3W9y1-YT0tAhWMXwFWDowxoSPHETfU9ntOkta1QdOnfGyE_pKgKyyd0ivONm-9l3649cXd9KUtc3lzrkUOOVPwfrufTNOdhP93oaPzKYi3QrNtNsk?purpose=fullsizehttps://images.openai.com/static-rsc-4/RrB5B7Gjyr93PPXg7HpFlEi9JlmUF57R8_yfyXbZrXlT4G76nkHcQGccFj9-1YE-GyT4XNb7GtjradAS2_x4qhTyfnxefk6iyvTJQpR2Cv9MwI7eHCuBcY2TjQ_5bz5kNHg4zzwMxG4GWXVgS0RGVZZHZ27AuHNi7Bh-pQ32ghCQ8Y-fBicbG9fCKzmJja-3?purpose=fullsize
2. Applications of AO168 in Food Contact Materials

AO168 is widely used in:

  • Food packaging films
  • Beverage caps
  • Microwave food containers
  • Fresh-keeping packaging
  • High-barrier packaging

Its key advantages include:

  • Low volatility
  • Low odor
  • Excellent processing stability
  • Strong synergy with primary antioxidants

Food Packaging Application Photos

https://images.openai.com/static-rsc-4/YKkI__YfDw7Vlb1uy4xjtuYn4PppwTDMRJQbaFVII-mKtW3cQrm4t3P7BljQWR9Dxfzw-W2oo6c2ztoc8tzvim5EzHrvVaZzWXlMxngQOIvtfU6U2mR00eg80yNtgLbcQgxNuiU4Y5VBOjD40MEas1dRTG89ZCl-JkUQahRgOz5J8O05_8QIJFe5z5iSvQi3?purpose=fullsizehttps://images.openai.com/static-rsc-4/l-_NTpX02_e4FE9fbDjtzP-_h-a8vdt9MkM9vj3aBqoT0zyjlTBM5n74_kBxOTtsP2jSjzbmAtdQHhbu2Pejld9K8FNkBVSUolLhvyZzNYSPyW-UfX_TcPHQEfYpPKeDwszuca23HW7LC4pwq841lNrfoGvl0afgKHXjWbUi2UsVt_-vQ2peSDArM2nxXOfL?purpose=fullsizehttps://images.openai.com/static-rsc-4/k-Q0WZ_fwRafk7_FKjJdEfkh8T9vWSruNT9-jsCTrNZj-VXDAsSYr2vxK0KLN9Az8tOj6m7GeDT1ouf0aS2GeL9BV6JxzGrVQmg7JLn6Pk2zfi2qpKRQRnso6DM02bVfV_6NdHNM0iLZJnalIPhinM4UWlNRnqELjG5b1ibTl0FT13BR-N6oS0Och1OVny42?purpose=fullsize
FDA and Food Contact Regulatory Requirements

When AO168 is used in food contact materials, it typically needs to comply with:

  • U.S. FDA food contact regulations
  • EU 10/2011
  • REACH
  • RoHS

Recent studies indicate that:

Migration control

of AO168 and its degradation byproducts is receiving increasing attention.

As a result:

High-purity AO168 is becoming an industry trend

3. Applications of AO168 in Medical Materials

Medical plastics require even stricter stabilization systems because they often undergo:

  • Steam sterilization
  • Ethylene oxide sterilization
  • Long-term human contact
  • Extended storage periods

Applications include:

  • Infusion devices
  • Syringes
  • Medical tubing
  • Hemodialysis materials
  • Medical packaging

Medical Material Application Photos

https://images.openai.com/static-rsc-4/wQY0MK09eeUi3GwqYCM072a0_s5F4MGDQqfZcjoqYB6ifHItcWLU7WwSLnC5835TRBs7c9b9VIzFjT9fNyoSnqmIwTdf4dJ29MGyvIbaSrKbVOVmGuHn20F3E5BEKfjAM5vBeEmyGR9NDw8T5ZDc7leK8s_J75cEfvtwB6PrPdPW6nGSTLMje76BiREnnz30?purpose=fullsizehttps://images.openai.com/static-rsc-4/SVxdhka0PDNH0n1eMFsF1oTe9MU6-0axHm_ijpGatkiEsGwEi50MGj6cCSoyMHAFRQoZztmU7z2ep910AJ1PXXNGmPJBgi8ZXFIfVHSavC70i2JQXEpOT7fGQBQI0XXZFlnSfKp7aXom9YYZteZLTq2dSBWImazRI4RPas6ba6sV9W-vUQ3uVNE1hqdfTlG3?purpose=fullsizehttps://images.openai.com/static-rsc-4/uyQhX2q1cV-V_T8X0C593xy64FQPin8QFBVceiGV5AzfjvPfnvJoiSTd_uwPi2uMcv-2AkQvUzzCvFNjYlue_hnADNX5WVahzEdc8Y4nwVlfwBojdgrhVnCcLoxB3Gje3MdRXrSC_obqTVDA-Jg7aWiWKFgpYoOav6bqGff-JC7RQt2642VyROCr0bdMLTfZ?purpose=fullsize
4. Future Purity Requirements for AO168

Traditional industrial-grade AO168 generally has:

Purity ≥99%

However, future medical and food-grade markets may increasingly require:

Application Area Future Recommended Purity
General plastics ≥99%
Food contact materials ≥99.3%
High-end food packaging ≥99.5%
Medical materials ≥99.5–99.8%
Advanced medical devices ≥99.8%

Why Higher Purity Will Be Required

Because:

Impurities and degradation byproducts

may lead to:

  • Increased odor
  • Higher VOC levels
  • Yellowing
  • Increased migration risks

In particular:

  • Free phenols
  • Oxidation byproducts
  • Hydrolysis impurities

can affect:

Food safety and biocompatibility

5. Future Certifications and Compliance Requirements

Future high-end AO168 products may require:

Certification / Regulation Purpose
FDA Food contact safety
EU 10/2011 EU food contact compliance
REACH European chemical regulation
RoHS Restriction of hazardous substances
ISO 10993 Medical biocompatibility
USP Class VI Medical plastic testing
GMP systems Medical and food manufacturing management

6. Future Development Trends of AO168

Future market demand for AO168 will increasingly focus on:

  • High purity
  • Low VOC
  • Low migration
  • Low odor
  • High hydrolysis resistance
  • Long-term stability

In particular:

Medical and food contact materials

will become one of the most important high-end application areas for AO168.

7. Why Choose Ecochem China AO168?

In medical and food-contact applications, AO168 is not just a conventional additive.

More importantly:

Stability and purity control are critical

Advantages of Ecochem China AO168

1. High Purity Control

We focus on:

  • High purity
  • Low impurities
  • Low free phenol content

in our AO168 product systems.

2. Excellent Hydrolysis Resistance

Our AO168 maintains stability under:

  • High humidity
  • High-temperature processing
  • Long-term storage

conditions.

3. Low VOC and Low Odor

Suitable for:

  • Food packaging
  • Medical plastics
  • High-end eco-friendly materials

applications.

4. Stable Batch Quality

Ecochem China strictly controls:

  • Raw materials
  • Production processes
  • Packaging and storage

to ensure consistent and reliable supply quality.

Ecochem China AO168 Product Photos

https://images.openai.com/static-rsc-4/RAglIhsIHQnqz2Y_TmolrTaGiJWB2ijhtqrhoBcT1zbonotTHv-cHxbfpmcqX2ihXASKXHfoCJqIKMfOkUEieewTEyE8IXlB-SqFJCbtOi5CterHyvTd_7-KeCtwxNy3yaqwOzsS1UISybb1oZ2_IS9iyaujftGqmUWJ_IUGNTWGKwhJUzWgHcvQChx5Dd9x?purpose=fullsizehttps://images.openai.com/static-rsc-4/oITMo2DWWjepR16ieIJaBtwuvLgG_rh1HjPUShtbeu2L41BJDonYF2d-LqUe-Yh1MaJZxEAm5OZ2jEQP9fsK8yJVj9L6-P6twD4o_ab9opShHRUmwJrAvxCpoSnaY40YLoUVUw6n5TMy36CIvppwSwqbMfzx_H0vE-m_Ai-A7AyDP3Bts6Nhi8ZDz8zV6ogc?purpose=fullsizehttps://images.openai.com/static-rsc-4/xrUjkTi1xYCYFZPQ2uea2sj3Bam4BNx3n1q3Jnp783jl8L3UkrhY1yzcflJZG-ZmhX7fZiXVUIN4FMn4gySvRKg0CgZwEKHud5x-5x-5TycKLxNQdrMnhhPLGLrGvZb9TGUz5bDXe9b_6vTj9zudp48InPDK7gU5f_d2LSvg_j1tajFrmnn_IjV5oODg5AU0?purpose=fullsize
8. Conclusion

As global:

  • Food safety regulations
  • Medical regulations
  • Environmental standards

continue to become stricter,

AO168 is evolving from a:

General-purpose antioxidant

into a:

High-purity, high-safety, and high-stability additive

In the future, medical and food-contact applications will become one of the most important premium markets for AO168.

Contact Us

Ecochem China

Website: www.ecochemchina.com

Email: info@ecochemchina.com

WhatsApp: +86-18921308539

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